Abstract
Summary
The effect of BAPN on traumatized and nontraumatized periosteum in rats of 1, 3, or 15 months of age was studied. The BAPN caused marked hypertrophy of nontraumatized periosteum in 1-month old rats but not in 3- or 15-month old rats. Response of traumatized periosteum to BAPN was similar in all 3 age groups. It is concluded that BAPN acts on newly formed collagen irrespective of age, but does not act significantly on mature collagen.
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