Abstract
Summary
The effect of chronic alcohol administration (10 weeks) on the glyceride content and enzyme profile of heart muscle, brain, and liver was examined in the dog. A significant increase (2.8-fold) in glyceride content of cardiac muscle was observed in the alcohol consuming animal, without concomitant changes in myocardial enzyme profile. Chronic alcohol administration resulted in a significant increase in activity of glycolytic and oxidative enzymes of the brain, but without parallel changes in the glyceride content of the brain. Ten-week long ethanol administration resulted in a 3.5-fold increase in glyceride content and a significant increase in activity of glycolytic and oxidative enzymes of the liver.
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