Abstract
Summary
An in vivo method, using the mouse as the experimental animal, for assessing the formation of a hemostatic platelet plug has been presented. Six compounds were tested, and the results indicate the activity observed correlates with the known activity of these compounds both in man and the experimental animal. Furthermore, it was observed that in vitro activity does not necessarily parallel in vivo effectiveness.
Get full access to this article
View all access options for this article.