Abstract
Summary
An examination of hexosemonophosphate shunt dehydrogenase activity in the rat exudate polymorphonuclear leukocyte reveals an exceedingly high NADPH generating capacity which is not modified by changes in composition of diet or alterations in thyroid status of the animal. This is in marked contrast to the hepatic shunt dehydrogenases which show marked alterations in response to the above stimuli. Thus, leukocyte HMPS dehydrogenase activity cannot be used as a peripheral index of hepatic shunt dehydrogenase activity.
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