Abstract
Summary
It is concluded that reaction products obtained by acetaldehyde treatment of certain biologically active amines manifest cerebrocortical EEG stimulant activity significantly greater than the parent compounds. We postulate that such products may indeed be formed endogenously, perhaps especially in pathologic conditions, to the extent of producing enhanced CNS stimulation. This further supports the hypothesis that prolonged CNS hyperstimulation induced by biochemical errors, may be etiological in some schizophrenic states.
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