Abstract
Summary
Exposure of rabbit liver slices to chlorpromazine in concentrations of 10-3 M, led to appreciable leakage of GOT and GPT into the surrounding medium. Promazine, in equal concentrations did not lead to an identifiable degree of leakage of these enzymes into the medium. The different effect of the two drugs on this system parallels what is known about their potential hepatotoxic effect in humans.
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