Abstract
Summary
In the rat, the intravenous administration of several rare earth metals (Ho, Tm, Dy, Er) induces an accumulation of calcium salts at sites treated with a histamine liberator, polymyxin. This reaction is obtained only with medium doses (3 mg) of metals; smaller (1 mg) and larger doses (5 and 8 mg) were inactive in this respect. The intensity of splenic calcification is directly proportional to the amount of rare earth administered.
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