In Vivo Lipogenesis in the Domestic Chicken

Abstract

Summary

The ability of chicks to utilize glucose-U-¹⁴C and acetate-1-¹⁴C as substrates for lipid synthesis has been studied. Chicks readily incorporated glucose and acetate carbon into fatty acids and nonsaponifiable lipids of liver and adipose tissue. Glucose-U-¹⁴C was also utilized for glyceride-glycerol formation. The relative importance of adipose tissue and liver as sites of fatty acid synthesis was estimated. Chick adipose tissue was found to be of minor importance as compared to liver, accounting for no more than 30% of total fatty acid synthesis.