Abstract
Conclusions
Daily intragastric administration of 50 mg/kg of cloxacillin, dicloxacillin, and leucomycin beginning 16 hours postintravenous challenge with a penicillinresistant, phage type 80/81 staphylococcus was followed by comparable results in most parameters measured. Only in duration of obvious clinical illness were differences noted in that leucomycin-treated monkeys did not appear well until 19-45 (mean 35) days after institution of therapy as compared to 9-27 (mean 16.6) and 7-24 (mean 14.1) days, respectively, in those treated with cloxacillin and dicloxacillin, respectively.
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