Abstract
Summary
The sensitivity to rubella virus of 96 lots of AGMK tissue culture was evaluated using the enterovirus interference technique. Wide variation in sensitivity was found leading to the classification of 32 of the lots tested as resistant to rubella virus. The use of these resistant lots of tissue culture for the isolation or titration of rubella virus would lead to invalid test results. Appropriate controls are needed to assure the validity of studies in which rubella virus is detected with African green monkey kidney tissue culture.
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