Abstract
Summary
A method is described for producing a narrow region of irradiation damage in the rat thymus bounded by normal thymic tissue. The mitotic and pyknotic indices of the shielded area of the thymus are comparable to those in normal thymic tissue indicating that the shielding is effective. The pattern of repopulation of the irradiated thymus is described. The source of the cells responsible for the repopulation is unknown; however, it is evident that an extensive migration of small thymocytes from the unirradiated area of the thymus into the irradiated area does not occur.
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