Abstract
Summary
Twelve rats were subjected to hemorrhagic shock. Histochemical study of the liver revealed increased adenosine triphosphatase and glucose-6-phosphatase activity when compared to controls. The reason for these alterations may be either an actual increase in enzymes in the parenchymal cells or altered histochemical reactivity due to cell necrosis, changes in membrane permeability, or deranged intra and extracellular ionic concentrations as a result of hypovolemia. The increased enzyme activities relate logically to altered carbohydrate metabolism and fluid dynamics in shock.
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