Abstract
Summary
Extracts of thymic tissue from syngeneic donors restored the immunologic capacity of neonatally thymectomized C57BL mice. Dissociated spleen cells of thymic-extract treated mice evoked a GVH reaction in newborn BALB/c mice. In contrast, splenic extracts were ineffective. Thymic extracts, however failed to lower the frequency of “wasting” with consequent death; neither did overt lymphoid regeneration occur in these treated mice thymectomized at birth.
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