Abstract
Summary
Rabbit antisera directed against cultured mouse lymphocytic leukemia L1210 cells as well as those directed against the ascitis form were shown to be immunosuppressive when injected into mice prior to immunization with sheep erythrocytes. The extent of immunosuppression was comparable to the one induced by injection of antisera directed against mouse spleen and lymph node antigens. The degree of immunosupression was quantitated by assaying the number of antibody forming cells by plaque formation in a sheep erythrocyte medium, and by titration of humoral hemagglutinins.
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