Abstract
Summary
Although young female rats of the Sprague-Dawley and Osborne-Mendel strains are quite vulnerable to the induction of mammary cancer by intragastric instillation of 7,12-dimethylbenz (a) anthracene and rats of Fischer, Marshall, and Long-Evans strains are relatively resistant, the fatty acid composition of mammary glands from rats of these five strains were comparable. A sex difference was noted in three strains with males having a somewhat greater proportion of 18:2 (linoleic acid) and a lower proportion 16:1 (palmitoleic acid) than females. The phospholipid levels of the breasts tissue of both male and females in all five strains were quite low relative to the total lipid.
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