Abstract
Summary
Adult squirrel monkeys maintained on a commercial chow demonstrated an impaired carbohydrate metabolism as evaluated by diagnostic tolbutamide and glucose tolerance tests. The possibility that the diet was deficient in trivalent chromium was investigated. The diet of normal and impaired monkeys was supplemented by the addition of trivalent and divalent chromium to the drinking water. The trivalent chromium supplementation produced an improvement in the tolbutamide and glucose tolerance responses of impaired monkeys when the drinking water was maintained at neutral pH but not at mildly acid pH. Normal monkeys supplemented with divalent chromium resulted in the appearance of impaired responses to tolbutamide and glucose tolerance tests.
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