Abstract
Summary
In acute experiments, administration of puromycin to adrenalectomized or intact mice inhibited the lymphopenic action of cortisol, whereas injection of 6-dimethylaminopurine, a puromycin analogue, did not prevent this response to cortisol. It is suggested that protein synthesis is an essential preliminary or accompanying process for the manifestation of the lymphopenic activity of glucocorticoids.
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