Abstract
Summary
The effect of phytohemagglutinin (PHA) on skin allograft survival in mice of two strains, DBA/2 and C57Bl/6J has been studied. The administration of PHA prior to grafting significantly increased graft survival time in both strains. No increase in survival was observed if PHA was given 24 hours after grafting. Likewise no differences were observed in second set skin graft survival between PHA treated mice and untreated controls. No toxic effects of PHA were noted in any of the treated mice at. the dosages and times of administration used.
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