Abstract
Summary
The induction of tryptophane pyrrolase and of tyrosine-α-ketoglutarate-transaminase with cortisol is altered in regenerating liver of hypophysectomized rats as compared to normal liver. While there is a decrease in induction of tryptophane pyrrolase 24 hours after hepatectomy a marked increase in the response of tyrosine transaminase activities of cortisol is found during the entire period of regeneration. The onset of mitotic activity during liver regeneration is delayed in hypophysectomized animals. By application of growth hormone it can be brought back to normal. This variation of the mitotic activity, however, has no influence on the time course of the changes in the induction of the two enzymes.
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