Abstract
Summary
The screening of maternal sera for lymphocytotoxic antibodies against a panel of 10 cells showed a 46.7% overall incidence of antibody formation. Positive reactions were obtained with 25% of the anti-sera obtained from women after a single pregnancy and 68% with antisera from women having had 8 or more pregnancies. As judged by the number of panel cells with which an antiserum reacts, there was no discernible tendency toward decreasing specificity with increasing numbers of pregnancies. It was observed, however, that antisera from first and second pregnancies differed in specificity from those antisera obtained after 3 or more pregnancies. A basis for this, and related observations, is discussed.
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