Abstract
Summary
Survival time was increased over 90% in mice with hereditary muscular dystrophy treated orally with a serotonin antagonist, methysergide bimaleate. There was a concurrent increase in body weight in treated animals. Short term treatment for 3 weeks with the drug caused a significant enlargement of the ovaries of dystrophic mice, but had no effect on body weight or other endocrine organ weights of normal mice.
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