Abstract
Summary
Hypophysectomy or castration of male rats results in a diminution of biosynthetic enzymic activities and tissue concentrations of ascorbic acid to levels characteristic of females. The data support the hypothesis that the sexual difference in tissue concentration of ascorbic acid in intact rats is dependent upon a difference in the rate of hepatic biosynthesis. The sexual difference in hepatic enzymic activities is interpreted to be dependent upon testicular secretion of androgens.
Get full access to this article
View all access options for this article.