Abstract
Summary
The chronic, disseminated inflammatory reaction observed in rats following a single intradermal injection of Freund's-type adjuvant was associated with a mild, non-progressive anemia which morphologically, biochemically and kinetically resembled the anemia associated with chronic disorders in man. It is suggested that “adjuvant disease” in the rat is an appropriate experimental model in which to study the complex pathogenesis of this distinctive but not uncommon form of anemia in man.
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