Abstract
Summary
A sexual influence on the enzymes in the biosynthesis of ascorbic acid, and on the tissue concentrations of total ascorbate has been shown by comparisons between male and female rats. Males have significantly higher activities for the 4 hepatic enzymes assayed, and significantly higher ascorbate concentrations in 6 of the 8 tissues analyzed. The higher male enzymic activities at the sub-cellular level are thought to be the molecular basis for the higher concentrations of ascorbic acid at the tissue level.
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