Abstract
Summary
Serial plasma HGH concentrations were measured, in 18 normal subjects, following continuous intravenous glucose infusion performed for periods of 3, 10, 20 and 30 minutes. In 5 of 8 cases infused for 3 minutes, no rise of plasma HGH was observed in spite of the rapid fall of blood glucose with (4 cases) or without (1 case) its reduction below the fasting level. The 3 other cases infused for 3 minutes and all 10 cases of 10, 20 and 30 minutes'infusion showed definite rise of plasma HGH at 90-180 minutes following the infusion. From the results obtained, it appears that the falling blood glucose per se is not a direct stimulus, and the reduction of blood glucose below the fasting level is not necessarily a stimulus to HGH secretion.
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