Abstract
Summary
1. Two doses of a partially purified, concentrated, formalin-killed epidemic typhus vaccine yielded excellent antibody responses in guinea pigs and in man. Even a single dose of this vaccine elicited an appreciable antibody response in man. 2. The compatibility of the epidemic typhus vaccine with a formalin-killed Q-fever vaccine administered as a mixture has been established in both guinea pigs and in man. 3. The C. bureti component of the combined vaccine definitely serves as an immunologic adjuvant for the epidemic typhus antigen in guinea pigs and may enhance the antibody response to the epidemic typhus component to some degree in man.
Get full access to this article
View all access options for this article.