Abstract
Summary
Lactate dehydrogenase (LDH) isozyme patterns in the blister fluid of cantharidin-produced blisters, epidermis, dermis. leucocytes, platelets, and serum have been studied. Blister fluid collected 7 hours after cantharidin application contained mainly LDH5 with some LDH4. LDH2 and LDH3 also appeared in blister fluid collected 12 hours or longer after application of cantharidin. This finding is consistent with the hypothesis that LDH in cantharidin-produced blisters is derived initially from epidermis and is later augmented from leucocytes or platelets.
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