Abstract
Summary
1. When mice bearing established, solid Ehrlich carcinomas were treated with pentaerythritol tetranitrate, there was an increase in the localization of Evans blue dye in the tumors. Epinephrine caused a decrease in the dye recovered from the tumors. 2. When mice bearing solid Ehrlich tumors were treated with pentaerythritol tetranitrate, heterologous antitumor serum (adsorbed) and normal guinea pig serum, 60% of the tumors regressed if treatment was continued for 5 weeks or longer. The administration of guinea pig serum may have been unnecessary.
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