Abstract
Summary
The saluresis of mercaptomerin and ethacrynic acid in dogs was measured in terms equivalent to urinary osmotic pressure and electrical conductivity. When converted into identical units (millimols or milliequivalents of NaCl per liter), these concentrative properties are shown to provide unique pharmacologic parameters of renal function such as the relative salinity or ionic fraction of the total solute concentration. In conjunction with specific electrolyte analyses, e.g., Na, K, and Cl, expressed in similar equipollent units (mEq/l), other singular relationships in urinary function are demonstrable.
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