Effect of Aldosterone on Transmembrane Potentials of Frog Skeletal Muscle. ∗

Abstract

Summary

Resting potentials of frog muscle fibers incubated in normal or high-potassium Ringer's solutions are maintained for longer periods of time by the addition of aldosterone. This response is absent in ouabain-Ringer's solution. Although based upon separate groups of muscles, the results indicate that muscle fibers in high-potassium Ringer's solution are slightly hyperpolarized when ouabain also is present.