Abstract
Summary
Aortic blood from normal, sham-splenectomized, and splenectomized rats was incubated with tritiated thymidine (2 μc/ml) for 1 hour at 37°C and the labeling incidences for the buffy coat leukocytes determined autoradiographically. It was found that a small percentage of mononuclear cells in the peripheral blood of normal rats were capable of incorporating tritiated-thymidine. Following splenectomy the numbers of these cells increased more than 4-fold for 23 days post-operation. The labeled cell types are described and possible causes for their increase in numbers after splenectomy are discussed.
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