Abstract
Summary
Shope virus-induced papillomas of domestic rabbits were cultivated in vitro and were subjected to immunofluorescent investigation. Two morphologically different cells, round or polygonal cells and triangular or columnar cells, were observed to grow out of explanted papilloma tissues. Among them, the majority of round or polygonal cells exhibited intense fluorescence reaction in nucleus. A certain number of triangular or columnar cells also reacted with specific fluorescence in nucleus but the intensity of the staining was weaker and less conspicuous. The implication of these findings was discussed in connection with previous immunofluorescent studies on the tumorous tissues of the Shope system.
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