Abstract
Summary
The ability of erythropoietin to stimulate Fe59 incorporation into heme was confirmed. A method of bone marrow culture was designed in order to assay erythropoietin in vitro. A log-dose response relationship was demonstrated with a lower limit of sensitivity of 0.05 units/ml. The effect of erythropoietin in vitro was blocked by erythropoietin antibody, trypsin, and actinomycin D.
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