Abstract
Summary
The L chain patterns of reduced and alkylated γ-globulin preparations from splenectomized, irradiated and normal rabbits were compared by starch gel electrophoresis. Animals irradiated with their spleen shielded produced γ-globulin with L chains similar to those of splenectomized and normal rabbits. Thus, the L chains formed in the spleen apparently do not differ electrophoretically from the L chains of γ-globuln formed in other organs.
I wish to thank Dr. F. Haurowitz, under whose supervision this study took place, for helpful discussion and suggestions, L. Hopper for technical assistance, and Dr. Charles D. Barnes for help and advice in irradiation of the animals.
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