Abstract
Summary
Acid deoxyribonuclease activity was measured in rat kidney tissue divided into the various renal segments: outer cortex (O.C.), inner cortex (I.C.), outer medulla (O.M.) and inner medulla (I.M., papilla). In terms of total activity, the O.C. had the highest enzyme content. The activity of the I.C. was considerably less and the medullary segments had the lowest values. If freeze-thaw procedures were not utilized, all segments except the papilla markedly decreased in enzyme activity. The enzyme values of the cortical segments were increased by lowering the sucrose content of the homogenate media. Those findings suggest that in addition to regional variation of activity, the relationship of acid deoxyribonuclease to the cell is different among the renal segments.
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