Abstract
Summary
Rats were injected with arachi-donic-1-C14 acid and the serum, liver, and testicular lipids examined at different time periods. The liver, at 1 hour, was found to contain 35% of the injected C14-activity. Arachidonic acid was preferentially incorporated into the liver and testicular phos-pholipids and the serum cholesterol esters. A rapid turnover of liver and serum arachidonic acid was observed (turnover time 18-24 hours). Long chain fatty acids derived from arachidonic acid were present in appreciable amounts only in the testes. The significance of these findings in relation to the metabolism of arachidonic acid is discussed.
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