Abstract
Summary
Hydrazine treatment resulted in increased levels of liver protein and RNA in rats at 24 hours following a single sub-convulsive dose of the compound. These changes were not observed as early as 4 hours after hydrazine treatment. However, increased levels of liver DNA were observed at 4 hours as well as at 24 hours in comparison to control values. These results might suggest that hydrazine treatment produced an initial aberration in liver DNA metabolism which resulted in subsequent alterations in the RNA and protein content of that organ.
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