Inhibition of Inorganic Phosphate Transport by Amino Acids in Rat Kidney-Cortical Slices in vitro . ∗

Abstract

Summary

The net accumulation of (³²P) inorganic phosphate in rat kidney cortex slices in vitro is inhibited by addition to the incubation mixture of L- or D-amino acids. In contrast with L-(¹⁴C) alanine, there was no net transport of D-(¹⁴C) alanine. Possible mechanisms of the inhibitory effect are discussed.