Amino Acid Composition of Three Immunological Types of Foot-and-Mouth Disease Virus

Abstract

Summary

There were significant differences in several of the 18 amino acids of foot-and-mouth disease viruses—immunologi-cal types A₁₁₉ ^CK, O₉ and C₃—which had been passed only a few times in tissue cultures. In addition, low passage A₁₁₉ ^CK virus differed from high passage A₁₁₉ virus in the 3 amino acids— glycine, tryptophan and tyrosine. This difference was correlated with previous findings concerning virulence, electrophoretic mobilities and degradation temperatures.