Abstract
Summary
Thermal neutron activation has been applied to the analysis of gold in biological samples. A convenient procedure is described for measurement of gold with a standard deviation of ± 5% in the range of 0.05 to 40.0 μg/ml. The tissue distribution and excretion of gold injected in rats is dependent upon the nature of the gold carrier. Mobilization of preinjected gold by various agents may enhance excretion but causes simultaneous redistribution of the metal in tissues. D,L-penicillamme, the most effective of a group of -SH containing gold binding compounds studied, decreased the gold content of spleen and lung but caused an increased gold deposition in liver and kidney during mobilization of predeposited tissue gold.
Get full access to this article
View all access options for this article.