Abstract
Summary
18F and 85Sr administered intravenously in rabbits and dogs yield the same information as 47Ca, insofar as early distribution and kinetics of tissue uptake affect “bone scanning” with external gamma scintillation detectors. Uptake by bone spongiosa exceeds that by compacta, Muscle and skin contain large fractions of the total activity during the first hour, but muscle content drops rapidly. 99mTc as pertechnetate ion does not behave like the bone seeker, but closely parallels bromide ion, 82Br, in its early distribution throughout leg tissues.
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