Lipid Variations Caused by Pteridine Deficiencies in Crithidia fasciculate ∗

Abstract

Summary

We have shown by alteration in ¹⁴C-acetate incorporation into lipid fractions during pteridine deficiencies that both un-conjugated and conjugated pteridmes affect lipid metabolism in C. jasciculata. The most obvious change appears as an alteration in the chromatographic profile of acetate incorporation into the lipid fractions concomitant with these deficiencies, i.e., the disappearance of label from the cardiolipin fraction and appearance of label into new fractions whose nature depends upon whether the deficiency is of conjugated or unconjugated pteridines.