Abstract
Summary and conclusions
Rats were maintained on 40% butter, 40% corn oil and control diets for 2, 4 and 6 weeks. Rats from each diet were traumatized in the Noble-Collip Drum so as to compare plasminogen activation. Serum proteolytic activity and cholesterol levels were determined. Differences in weights of the comparably dieted animals were negligible. Serum cholesterol levels were markedly higher in those fed high fat diets with 5% cholesterol than in rats on control diets. Trauma caused significantly increased serum proteolytic activity and serum cholesterol levels in all groups. The diet administered produced moderate hypercholesterolemia which did not significantly alter the serum proteolytic activator or plasmin activity of normal or traumatized rats.
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