Abstract
Summary
The rates of oxidation of acetate to C02 were estimated by using 1-C14 and 2-C14 labeled acetate and measuring both blood and expired C1402. Following 1-C14 labeled acetate infusion, the half life of blood and expired C1402 was about 76 minutes indicating a mean turnover time of acetate carboxyl to pool C02 of about 110 minutes.
The half lives of 2-C14 labeled acetate were 135 minutes and 195 minutes respectively. The half life of the pool acetate was 1.2 minutes; turnover time 1.7 minutes; turnover rate 3.4 meq per hour and pool size 6.0 meq per sheep.
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