Abstract
Summary
A simple method for estimating the relative number of viral particles in thin sections of tissue is described. By this method particle frequency was defined as the presence or absence of particles within a specified sectioned area, which was dependent upon the number of nuclear sections examined with the electron microscope. This technique was applied to CFWW axenic mice inoculated with human leukemic cells. It was observed that the number of viral particles appeared to increase as the cells were serially transferred in mice.
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