Abstract
Summary
The colloidal nature of ICG in aqueous solutions has been characterized by dialysis, ultranltration and spectral absorption measurements. Using gel filtration (Sephadex G-100 and G-200), ultracentrifu-gal flotation, density gradient sedimentation, immuno- and paper-electrophoretic methods, evidence has been accumulated to show that 90% of the ICG in canine serum and 80% of the dye in human serum is associated with globulins. Comparable values for BSP are 60% and 30%. The data suggest that the α1 group of lipoproteins has a higher affinity for the dyes than albumin.
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