Abstract
Summary
Three γA myeloma proteins were encountered which were very similar but differed markedly in antigenic properties from the bulk of γA proteins. Several antisera from rabbits as well as primates served to distinguish these proteins as belonging to a well denned subgroup. The distinguishing characteristics were shown to be properties of the heavy chains. A general but not absolute relationship to electrophoretic mobility was demonstrated.
Addendum. Exchange of γA proteins with Drs. Vaerman and Her emails and also with Drs. Feinstein and Franklin indicate that these two groups of workers have also observed the same subgroups.
The authors are indebted to Dr. Thomas B. Tomasi for isolated γA proteins from salica, colostrum and ascitic fluid as well as for certain γA myeloma proteins and to Drs. R. S. Beckett and C. Rankin for a number of the γA myeloma sera.
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