Abstract
Summary
The heteroanthracenes acrifla-vine, eosin, Janus green, methylene blue, ribo-flavin, safranin and thionin inactivated ac-tinophage MSP2 when exposed to bright light. The extent of photoinactivation was determined by dye concentration, duration of exposure to light, ionic strength of the milieu, and availability of air. In general, combinations of photosensitizing dyes had an additive effect, indicating different mechanisms of action. The data suggest, however, that all of the dyes were damaging the phage deoxyribo-nucleic acid.
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