Gm and Inv Antigenic Character of Serum and Cerebrospinal Fluid IgG in Multiple Sclerosis. ∗

Abstract

Summary

Antigenic analysis of γ-globulins in the CSF of controls and patients with multiple sclerosis showed no gross deficiency in Gm or Inv typing. Concordant typing for Gm and Inv factors from serum and CSF identifies the antigenic completeness of IgG in both control and multiple sclerosis CSF. No support was obtained for the possibility that individuals with multiple sclerosis differ from controls in Gm or Inv(a) serotypes.