Abstract
Summary
Colloidal gold phagocytosis by rat liver slices was slight in oxalated rat plasma or serum; however, heparin addition markedly increased the uptake. Heparin also augmented the hepatic phagocytosis of human serum albumin aggregates from oxalated plasma. Other sulfated polysaccharides either had no effect, or only slightly enhanced, gold uptake. The mechanism of heparin action in promoting phagocytosis may be related to facilitation of opsonin-particle interaction.
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